| Rafael De Paula | P | 23.121 | San Diego Padres | San Diego Padres (MLB) | Traded from Yankees with Yangervis Solarte to Padres for Chase Headley |
| Tsuyoshi Wada | P | 33.152 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Jose Ramirez | 2B | 21.309 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Taijuan Walker | P | 21.344 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Bruce Billings | P | 28.247 | New York Yankees | New York Yankees (MLB) | Designated for Assignment |
| Kelly Johnson | dh | 32.151 | New York Yankees | New York Yankees (MLB) | DL-15 Strained left groin |
| Chris Leroux | RP | 30.100 | New York Yankees | New York Yankees (MLB) | Contract purchased from minors |
| Zach Walters | SS | 24.321 | Washington Nationals | Washington Nationals (MLB) | Recalled from Syracuse (AAA) |
| Ryan Zimmerman | 3b | 29.298 | Washington Nationals | Washington Nationals (MLB) | DL-15 Strained right hamstring |
| Phillippe Aumont | RP | 25.197 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Jeff Manship | SP | 29.188 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Designated for Assignment |
| Carlos Ruiz | c | 34.183 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from minor league rehab assignment |
| Carlos Ruiz | C | 34.183 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Kevin Siegrist | RP | 25.003 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from minor league rehab assignment |
| Kevin Siegrist | RP | 25.003 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Activated from DL |
| Gus Schlosser | P | 25.276 | Atlanta Braves | Atlanta Braves (MLB) | Recalled from Gwinnett (AAA) |
| Anthony Varvaro | RP | 29.265 | Atlanta Braves | Atlanta Braves (MLB) | Placed on Paternity Leave list |
| Jeff Francoeur | lf | 30.197 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from minors |
| Cameron Maybin | cf | 27.110 | San Diego Padres | San Diego Padres (MLB) | Suspended 25 games for testing positive for amphetamines |
| Marc Krauss | DH | 26.292 | Houston Astros | Houston Astros (MLB) | Recalled from Oklahoma City (AAA) |
| George Springer | CF | 24.307 | Houston Astros | Houston Astros (MLB) | DL-15 Strained right quad |
| C.J. Cron | 1B | 24.199 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Grant Green | 2b | 26.300 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Lumbar strain |
| Starling Marte | lf | 25.287 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-7 Concussion |
| Brent Morel | 3b | 27.093 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Matt Guerrier | RP | 35.355 | Minnesota Twins | Minnesota Twins (MLB) | Designated for Assignment |
| Ryan Pressly | RP | 25.220 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Joakim Soria | RP | 30.066 | Detroit Tigers | Detroit Tigers (MLB) | Traded from Rangers to Tigers for Corey Knebel and Jake Thompson |
| Corey Knebel | P | 22.240 | Texas Rangers | Texas Rangers (MLB) | Traded from Tigers with Jake Thompson to Rangers for Joakim Soria |
| Albert Almora | OF | 20.098 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Austin Bibens-Dirkx | P | 29.085 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Mitchell Boggs | RP | 30.159 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) |
| Randy Boone | P | 29.351 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Bryce Brentz | RF | 25.205 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Activated from disabled list |
| David Cales | P | 26.362 | Chicago White Sox | Birmingham (AA) | Activated from disabled list |
| Buddy Carlyle | P | 36.214 | New York Mets | Las Vegas (AAA) | Outrighted to minors |
| Fabio Castillo | P | 25.154 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Cody Davis | P | 24.002 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Taylor Davis | C | 24.237 | Chicago Cubs | Tennessee (AA) | Activated from disabled list |
| Miller Diaz | P | 22.031 | New York Mets | Savannah (A) | Activated from disabled list |
| Alex Dickerson | 1B | 24.058 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Carl Edwards | P | 22.324 | Chicago Cubs | Arizona Cubs (Rk) | Activated from disabled list |
| Ryan Fisher | 3B | 26.090 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Charles Gillies | P | 23.327 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Francisco Gracesqui | | 22.240 | Toronto Blue Jays | Lansing (A) | Assigned to Lansing (A) |
| Nick Greenwood | P | 26.299 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Preston Guilmet | RP | 26.362 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Jesse Hahn | P | 24.358 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Mitch Haniger | OF | 23.212 | Milwaukee Brewers | Huntsville (AA) | Activated from disabled list |
| Jacob Hannemann | CF | 23.085 | Chicago Cubs | Daytona (A+) | Assigned to Daytona (A+) |
| Kyle Higashioka | C | 24.094 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| T.J. House | P | 24.297 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Travis Jankowski | OF | 23.038 | San Diego Padres | Eugene (A-) | Assigned to Eugene (A-) |
| Steve Johnson | RP | 26.327 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) |
| Adaric Kelly | P | 21.234 | Toronto Blue Jays | Vancouver (A-) | Assigned to Vancouver (A-) |
| Jared Lakind | 1B | 22.136 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Rymer Liriano | RF | 23.033 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Josh Ludy | C | 24.096 | Oakland Athletics | Beloit (A) | Assigned to Beloit (A) |
| Dustin Martin | RF | 30.110 | Arizona Diamondbacks | Reno (AAA) | Activated from disabled list |
| Greg Miclat | SS-2B | 27.000 | St. Louis Cardinals | Palm Beach (A+) | Activated from disabled list |
| Joseph Monge | RF | 19.066 | Boston Red Sox | Lowell (A-) | Assigned to Lowell (A-) |
| Josh Mueller | P | 25.186 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Kevin Nolan | SS | 26.223 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Mike Olt | 3b | 25.330 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Jordan Pacheco | c-1B | 28.174 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) for rehab |
| Andy Paz | C | 21.199 | Oakland Athletics | Arizona Athletics (Rk) | Assigned to Arizona Athletics (Rk) |
| Kenny Peoples-Walls | | 20.341 | St. Louis Cardinals | State College (A-) | Assigned to State College (A-) |
| Adys Portillo | P | 22.216 | San Diego Padres | San Antonio (AA) | Activated from disabled list |
| Erasmo Ramirez | SP | 24.082 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Dae-Eun Rhee | P | 25.122 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Maximo Rivera | | 21.213 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Cameron Rupp | C | 25.298 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Sergio Santos | RP | 31.019 | Toronto Blue Jays | Buffalo (AAA) | Outrighted to minors |
| Ian Stewart | 3B | 29.109 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Matthew Taylor | P | 23.113 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Activated from disabled list |
| Phillips Valdez | P | 22.250 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Logan Vick | IF-OF | 23.274 | Cleveland Indians | Carolina (A+) | Activated from disabled list |
| Rowan Wick | OF | 21.256 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Alex Wimmers | P | 25.264 | Minnesota Twins | New Britain (AA) | Assigned to New Britain (AA) |
| Jair Jurrjens | RP | 28.175 | Colorado Rockies | Colorado Rockies (MLB) | Outrighted to minors |
| Stephen Pryor | RP | 25.000 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Yusuf Carter | c | 29.167 | Toronto Blue Jays | New Hampshire (AA) | Activated from disabled list |
| Edwin Fierro | P | 20.327 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to GCL Rays (Rk) |
| James Simmons | P | 27.297 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Jose Chavez | C | 19.076 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Aaron Vaughn | P | 22.220 | Houston Astros | Tri City (A-) | Assigned to Tri-CIty (A-) |
| Cameron Varga | P | 19.338 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Kyle Fischer | P | 23.162 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Ryan Leonards | SS | 23.001 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| J.P. Sportman | IF | 22.179 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| James Alfonso | C | 22.324 | Seattle Mariners | Everett (A-) | Assigned to Everett (A-) |
| Jared Miller | P | 20.336 | Arizona Diamondbacks | Hillsboro (A-) | Signed out of draft (Vanderbilt) |
| Algeni Mateo | C | 18.357 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees (Rk) |
| Caleb Beech | P | 21.096 | Atlanta Braves | Gulf Coast Braves (Rk) | Signed out of draft (Shelton State CC) |
| Connor Goedert | 3B | 20.221 | Houston Astros | Gulf Coast Astros (Rk) | Assigned to GCL Astros (Rk) |
| Gunnar Heidt | IF | 21.314 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Signed out of draft (College of Charleston) |
| Jeremy Rivera | SS | 19.174 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Signed out of draft (El Paso CC) |
| Leland Clemmons | OF | 21.036 | Kansas City Royals | Burlington (Rk) | Signed out of draft (Winston-Salem State) |
| Luis Nunez | P | 22.268 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Assigned to GCL Rays (Rk) |
| Algeni Mateo | C | 18.357 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to GCL Yankees (Rk) |
| Arismendy Ozoria | P | 23.350 | | | Announced retirement |
| Edwin German | p | 21.316 | New York Mets | New York Mets (MLB) | Signed to Minor League Contract |
