| Domonic Brown | lf | 26.305 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from Paternity Leave list |
| Brandon Belt | 1b | 26.075 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Logan Schafer | cf-lf | 27.299 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Nashville (AAA) |
| Cole Gillespie | rf | 30.014 | Seattle Mariners | Seattle Mariners (MLB) | Designated for Assignment |
| Corey Hart | 1b | 32.102 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Jonathan Sanchez | RP | 31.227 | - | | Released by Cubs |
| Brett Cecil | RP | 28.002 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Jeff Beliveau | P | 27.168 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Cesar Ramos | RP | 30.012 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Placed on Paternity Leave list |
| Justin Smoak | 1b | 27.211 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from minor league rehab assignment |
| Justin Smoak | 1b | 27.211 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Neftali Feliz | P | 26.063 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Joe Saunders | SP | 33.018 | - | | Released by Rangers |
| Joshua Fields | RP | 28.319 | Houston Astros | Houston Astros (MLB) | Activated from DL |
| Derek Dietrich | 2b | 24.351 | Miami Marlins | Miami Marlins (MLB) | DL-15 Strained right wrist |
| Jake Marisnick | cf | 23.096 | Miami Marlins | Miami Marlins (MLB) | Recalled from New Orleans (AAA) |
| Jair Jurrjens | RP | 28.156 | Colorado Rockies | Colorado Rockies (MLB) | Contract purchased from minors |
| Martin Agosta | P | 23.088 | San Francisco Giants | Arizona Giants (Rk) | Activated from disabled list |
| Hanser Alberto | SS | 21.260 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Vance Albitz | SS | 26.155 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Cory Aldridge | RF | 35.021 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Aaron Altherr | LF-CF | 23.171 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Andrew Barbosa | P | 26.229 | Arizona Diamondbacks | Arizona Diamondbacks (Rk) | Activated from disabled list |
| Clayton Blackburn | P | 21.179 | San Francisco Giants | Richmond (AA) | Activated from disabled list |
| Trent Blank | P | 24.307 | Colorado Rockies | Asheville (A) | Activated from disabled list |
| Royce Bolinger | OF | 23.326 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Matt Bowman | P-IF | 23.034 | New York Mets | Las Vegas (AAA) | Assigned to Las Vegas (AAA) |
| Yimmi Brasoban | P | 20.012 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Parker Bridwell | P | 22.337 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Lewis Brinson | OF | 20.057 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Juan Caballero | | 21.318 | St. Louis Cardinals | Johnson City (Rk) | Assigned to Johnson City (Rk) |
| Austin Chubb | C | 25.078 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Adam Duvall | 3B | 25.303 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) |
| Daniel Fields | CF | 23.162 | Detroit Tigers | Gulf Coast Tigers (East) (Rk) | Assigned to GCL Tigers (Rk) for rehab |
| Edwin Garcia | SS-2B | 23.125 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Christopher Grayson | RF-LF | 24.292 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Kevin Grendell | P | 20.316 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Evan Grills | P | 22.021 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Elian Herrera | lf | 29.153 | Milwaukee Brewers | Nashville (AAA) | Assigned to Nashville (AAA) |
| Blake Holovach | P | 23.099 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Jeffrey Inman | P | 26.223 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Paul Janish | 3b-2b | 31.265 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) |
| Tyler Kane | P | 21.315 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Jared King | OF | 22.266 | New York Mets | Gulf Coast Mets (Rk) | Activated from disabled list |
| Kameron Loe | RP | 32.297 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) |
| Nick Maronde | RP | 24.302 | Los Angeles Angels | Arkansas (AA) | Activated from DL |
| Kent Matthes | RF | 27.177 | Oakland Athletics | Midland (AA) | Activated from disabled list |
| Cory Mazzoni | P | 24.258 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Toru Murata | P | 29.045 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Shawn O'Malley | SS-2B | 26.189 | Los Angeles Angels | Salt Lake (AAA) | Activated from DL |
| Braulio Ortiz | P | 22.197 | Chicago White Sox | Birmingham (AA) | Assigned to Birmingham (AA) |
| Michael Quesada | C-LF | 24.153 | Minnesota Twins | Cedar Rapids (A) | Activated from disabled list |
| Jose Ramirez | P | 24.164 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Ryan Rodebaugh | P | 25.096 | Texas Rangers | Frisco (AA) | Activated from disabled list |
| Ben Rowen | P | 25.231 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Rob Scahill | RP | 27.139 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Justin Smoak | 1b | 27.211 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Ryan Strausborger | CF | 26.122 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Carlos Triunfel | ss | 24.127 | Los Angeles Dodgers | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Beck Wheeler | P | 25.203 | New York Mets | St. Lucie (A+) | Activated from disabled list |
| Adron Chambers | rf | 27.269 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Jason Donald | SS | 29.303 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Jeff Lorick | P | 26.199 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Mason Tobin | P | 26.362 | | | Released by Giants |
| Brian Goodwin | OF | 23.244 | Washington Nationals | Syracuse (AAA) | DL-7 Injured |
| Christian Villanueva | 3B | 23.015 | Chicago Cubs | Tennessee (AA) | DL-7 Injured |
| Timothy Sexton | P | 27.024 | | | Released by Padres |
| Jochi Ogando | P | 21.038 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Nick Avila | P | 25.309 | | | Announced retirement |
| Ruben Alaniz | P | 23.020 | Houston Astros | Gulf Coast Astros (Rk) | DL-7 Injured |
| Ryan Demmin | P | 26.090 | | | Announced retirement |
| Courtney Hawkins | OF | 20.234 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Frankie Montas | P | 21.105 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Jonathan Schwind | C | 24.035 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Juan Silva | LF | 23.177 | Cincinnati Reds | Bakersfield (A+) | DL-7 Injured |
| Taylor Lewis | CF | 24.198 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Tim Anderson | SS | 21.011 | Chicago White Sox | Winston-Salem (A+) | DL-7 Injured |
| Brandon Bayardi | OF | 23.219 | Los Angeles Angels | Burlington (A) | DL-7 Injured |
| Chris Flexen | P | 20.003 | New York Mets | Savannah (A) | DL-7 Tommy John Surgery |
| Zachary Bird | P | 19.355 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Caleb Kellogg | P | 22.031 | Baltimore Orioles | Gulf Coast Orioles (Rk) | DL-60 Injured |
| Chris Capuano | SP | 34.320 | Colorado Rockies | Colorado Springs (AAA) | Signed to minor league contract |
| Scott Elbert | P | 28.325 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from minor league rehab assignment |
| Jhoulys Chacin | SP | 26.179 | Colorado Rockies | Colorado Rockies (MLB) | Transferred to 60-day DL |
| Nick Buss | CF | 27.201 | Oakland Athletics | Oakland Athletics (MLB) | Designated for Assignment |
| Jason Hammel | SP | 31.305 | Oakland Athletics | Oakland Athletics (MLB) | Traded from Cubs with Jeff Samardzija to Athletics for Addison Rusell, Billy McKinney, Dan Straily and PTBNL |
| John Mcleod | P | 22.031 | Baltimore Orioles | Aberdeen (A-) | Signed out of draft (Wake Forest) |
| Derek Fisher | OF | 20.317 | Houston Astros | Gulf Coast Astros (Rk) | Signed out of draft (Virginia) |
| Mike Franco | P | 22.227 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Austin Young | P | 22.075 | Los Angeles Angels | Arizona Angels (Rk) | Signed out of draft (Virginia) |
| Brock Burke | P | 17.334 | Tampa Bay Rays | Gulf Coast Rays (Rk) | Signed out of draft (Colorado HS) |
| Chris Harvey | C | 21.116 | Pittsburgh Pirates | Bristol (Rk) | Signed as undrafted free agent (Vanderbilt) |
| Forrest Wall | 2B | 18.227 | Colorado Rockies | Grand Junction (Rk) | Signed out of draft (Florida HS) |
| John Curtiss | P | 21.090 | Minnesota Twins | Elizabethton (Rk) | Signed out of draft (Texas) |
| Jordan Romano | P | 21.074 | Toronto Blue Jays | Bluefield (Rk) | Assigned to Bluefield (Rk) |
| Kurtis Horne | P | 17.333 | New York Mets | Gulf Coast Mets (Rk) | Signed out of draft (British Columbia HS) |
| Patrick Baker | P | 20.323 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Signed out of draft (Anne Arundel CC) |
| Rafael Devers | 3B | 17.253 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to GCL Red Sox (Rk) |
| Raphael Ramirez | OF | 18.202 | New York Mets | Gulf Coast Mets (Rk) | Signed out of draft (Georgia HS) |
| Taylor Sparks | 3B | 21.092 | Cincinnati Reds | Billings (Rk) | Signed out of draft (UC Irvine) |
| Caleb Ferguson | P | 18.002 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed out of draft (Ohio HS) |
