| Joel Hanrahan | RP | 32.209 | Detroit Tigers | Detroit Tigers (MLB) | DL-15 Recovery from right elbow surgery |
| Danny Santana | SS | 23.177 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Chris Coghlan | 3B-LF | 28.319 | Chicago Cubs | Chicago Cubs (MLB) | Contract purchased from minors |
| Kyuji Fujikawa | RP | 33.286 | Chicago Cubs | Chicago Cubs (MLB) | Transferred to 60-day DL |
| Ryan Sweeney | CF | 29.072 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Strained right hamstring |
| Jacob Turner | SP | 22.348 | Miami Marlins | Miami Marlins (MLB) | Activated from DL |
| Jake Arrieta | SP | 28.058 | Chicago Cubs | Chicago Cubs (MLB) | Activated from DL |
| Hisashi Iwakuma | SP | 33.021 | Seattle Mariners | Seattle Mariners (MLB) | Activated from DL |
| Chris Leroux | RP | 30.019 | New York Yankees | New York Yankees (MLB) | Designated for Assignment |
| Logan Schafer | cf-lf | 27.237 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Activated from DL |
| Ryan Braun | lf | 30.168 | Milwaukee Brewers | Milwaukee Brewers (MLB) | DL-15 Strained right oblique |
| Elliot Johnson | 2b | 30.055 | Cleveland Indians | Cleveland Indians (MLB) | Designated for Assignment |
| Nick Hagadone | RP | 28.122 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Yan Gomes | c | 26.289 | Cleveland Indians | Cleveland Indians (MLB) | Placed on Paternity Leave list |
| Adam Eaton | lf | 25.148 | Chicago White Sox | Chicago White Sox (MLB) | DL-15 Strained right hamstring |
| Nate Jones | RP | 28.095 | Chicago White Sox | Chicago White Sox (MLB) | Transferred to 60-day DL |
| CJ Cron | 1B | 24.118 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from minors |
| David Freese | 3b | 31.005 | Los Angeles Angels | Los Angeles Angels (MLB) | DL-15 Fractured right middle finger |
| Luis Jimenez | 3B | 26.106 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Michael McKenry | c | 29.060 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from Colorado Springs (AAA) |
| Stolmy Pimentel | P | 24.091 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | DL-15 Right shoulder inflammation |
| Vincent Mazzaro | RP | 27.218 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Contract purchased from minors |
| Jared Hughes | RP | 28.303 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Skip Schumaker | rf | 34.090 | Cincinnati Reds | Cincinnati Reds (MLB) | Activated from DL |
| Roger Bernadina | cf | 29.325 | Cincinnati Reds | Cincinnati Reds (MLB) | Designated for Assignment |
| Chad Jenkins | RP | 26.133 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Will Anderson | P | 21.250 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Wil Browning | P | 25.237 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Francisley Bueno | RP | 33.059 | Kansas City Royals | Omaha (AAA) | Activated from disabled list |
| Lorenzo Cain | RF | 28.020 | Kansas City Royals | Omaha (AAA) | Assigned to Omaha (AAA) for rehab |
| Leonel Campos | P | 26.291 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Ben Carhart | 3B | 24.102 | Chicago Cubs | Kane County (A) | Activated from disabled list |
| Ian Clarkin | P | 19.078 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Ryan Cordell | OF | 22.033 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Caleb Cotham | P | 26.179 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| DJ Crumlich | SS | 24.010 | Pittsburgh Pirates | Bradenton (A+) | Assigned to Bradenton (A+) |
| Joel De La Cruz | P | 24.328 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Esmerling De La Rosa | | 22.354 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Abel De Los Santos | P | 21.163 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Bengie Gonzalez | SS | 24.107 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Riley Good | OF | 22.057 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Scott Hairston | lf | 33.343 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) for rehab |
| Brett Jackson | cf | 25.274 | Chicago Cubs | Iowa (AAA) | Activated from disabled list |
| Dan Jennings | RP | 27.016 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Keone Kela | P | 21.017 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Casey Kelly | SP | 24.211 | San Diego Padres | Lake Elsinore (A+) | Activated from disabled list |
| Jon Leroux | C | 23.226 | New York Mets | Savannah (A) | Assigned to Savannah (A) |
| Lucas Luetge | RP | 27.068 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Omar Luis | P | 21.202 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Eric Marzec | P | 26.111 | Milwaukee Brewers | Nashville (AAA) | Assigned to Nashville (AAA) |
| Josh McElwee | P | 24.325 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Reese McGuire | C | 19.062 | Pittsburgh Pirates | West Virginia (A) | Activated from disabled list |
| Yhoxian Medina | SS | 23.357 | Cleveland Indians | Carolina (A+) | Assigned to Carolina (A+) |
| Logan Moore | C | 23.254 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Zach Nuding | P | 24.035 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Carlos Quentin | lf | 31.248 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) for rehab |
| Michael Ramirez | C | 24.006 | Colorado Rockies | Colorado Springs (AAA) | Activated from disabled list |
| Reid Redman | IF | 25.162 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Tony Renda | SS | 23.099 | Washington Nationals | Potomac (A+) | Activated from disabled list |
| Zac Rosscup | P | 25.328 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Adam Russell | P | 31.019 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) |
| Jake Schrader | 1B | 23.063 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Corey Seager | SS | 20.006 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Activated from disabled list |
| Marcus Stroman | P | 23.002 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Nick Struck | P | 24.208 | Los Angeles Dodgers | Albuquerque (AAA) | Assigned to Albuquerque (AAA) |
| Gio Urshela | 3B | 22.205 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Charlie Valerio | C | 23.177 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Matt West | P | 25.163 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Marc Wik | CF | 21.289 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| JaDamion Williams | RF | 23.164 | Minnesota Twins | Cedar Rapids (A) | Assigned to Cedar Rapids (A) |
| Matt Wisler | P | 21.233 | San Diego Padres | El Paso (AAA) | Assigned to El Paso (AAA) |
| Alfredo Aceves | RP | 31.146 | New York Yankees | New York Yankees (MLB) | Contract purchased from minors |
| George Kottaras | c | 30.353 | Cleveland Indians | Cleveland Indians (MLB) | Contract purchased from minors |
| Yoslan Herrera | P | 33.005 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Yoslan Herrera | P | 33.005 | Los Angeles Angels | Los Angeles Angels (MLB) | Outrighted to minors |
| Frank De los Santos | P | 26.168 | Chicago White Sox | Chicago White Sox (MLB) | Recalled from Charlotte (AAA) |
| Brandon Morrow | SP | 29.281 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Torn tendon sheath, right hand |
| Jake Elmore | 2b | 26.323 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from minor league rehab assignment |
| Andy LaRoche | 3b | 30.264 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Buddy Carlyle | P | 36.133 | New York Mets | Brooklyn (A-) | Assigned to Brooklyn (A-) |
| John Lannan | SP | 29.218 | New York Mets | Las Vegas (AAA) | Placed on temporarily inactive list |
| Radhames Liz | P | 30.328 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Randy Boone | P | 29.270 | Toronto Blue Jays | New Hampshire (AA) | DL-7 Injured |
| Aaron West | P | 23.336 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Bobby Borchering | 1B-3B | 23.190 | Houston Astros | Lancaster (A+) | DL-7 Injured |
| DJ Baxendale | P | 23.146 | Minnesota Twins | New Britain (AA) | DL-7 Injured |
| Eric Stamets | IF | 22.221 | Los Angeles Angels | Arkansas (AA) | DL-7 Injured |
| Jarret Martin | P | 24.262 | Los Angeles Dodgers | Chattanooga (AA) | DL-7 Injured |
| Peter Mooney | SS | 23.257 | Toronto Blue Jays | New Hampshire (AA) | DL-7 Injured |
| Travis Witherspoon | CF | 25.017 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| David Holman | P | 23.337 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Dylan Unsworth | P | 21.222 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Eric Pfisterer | P | 23.350 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| JD Osborne | P | 23.171 | Houston Astros | Lancaster (A+) | Placed on temporarily inactive list |
| Oliver Garcia | P | 23.147 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Tyler Smith | IF | 22.307 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Andrew Beresford | P | 24.066 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Andry Ubiera | P | 20.346 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Chris Burgess | P | 23.252 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Assigned to extended spring training |
| Francisco Diaz | C | 24.043 | Pittsburgh Pirates | Jamestown (A-) | Assigned to Jamestown (A-) |
| Moises Sierra | rf | 25.221 | Chicago White Sox | Chicago White Sox (MLB) | Claimed off waivers from Blue Jays by White Sox |
| Matt Montgomery | P | 26.287 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Ray Black | P | 23.311 | San Francisco Giants | Augusta (A) | Activated from DL |
