| Edgmer Escalona | RP | 26.328 | Colorado Rockies | Colorado Springs (AAA) | Outrighted to Colorado Springs (AAA) |
| Walter Ibarra | SS-2B | 25.303 | | | Released by Yankees |
| Mike Blazek | RP | 24.167 | St. Louis Cardinals | Memphis (AAA) | Optioned to Memphis (AAA) |
| Sam Freeman | RP | 26.067 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Michael Wacha | RP | 22.060 | St. Louis Cardinals | Memphis (AAA) | Optioned to Memphis (AAA) |
| Matt Fox | P | 30.269 | New York Mets | Las Vegas (AAA) | Activated from temporarily inactive list |
| Jacob DeGrom | P | 25.072 | New York Mets | Las Vegas (AAA) | DL-7 Injured |
| Tom Cochran | P | 30.318 | Philadelphia Phillies | Lehigh Valley (AAA) | Activated from temporarily inactive list |
| A.J. Jimenez | C | 23.121 | Toronto Blue Jays | Buffalo (AAA) | Placed on temporarily inactive list |
| Matt Moore | SP | 24.073 | Tampa Bay Rays | Durham (AAA) | Assigned to Durham (AAA) for rehab |
| Chris Carpenter | RP | 27.247 | Boston Red Sox | Pawtucket (AAA) | Placed on temporarily inactive list |
| Corky Miller | c | 37.165 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) for rehab |
| Tommy Hottovy | P | 32.052 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Diego Moreno | P | 26.040 | New York Yankees | Trenton (AA) | DL-7 Right shoulder soreness |
| Jason Hammel | SP | 30.362 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) for rehab |
| J.R. Ballinger | P | 25.150 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Ryan McCurdy | C | 25.246 | Houston Astros | Corpus Christi (AA) | DL-7 Injured |
| Jorge Bonifacio | RF | 20.087 | Kansas City Royals | Northwest Arkansas (AA) | DL-7 Injured |
| David Colvin | P | 24.235 | Seattle Mariners | High Desert (A+) | DL-7 Injured |
| Cutter Dykstra | 2B-LF | 24.062 | Washington Nationals | Potomac (A+) | Placed on temporarily inactive list |
| Ali Williams | P | 24.053 | Kansas City Royals | Wilmington (A+) | Placed on temporarily inactive list |
| Taylor Cole | P | 24.010 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Saxon Butler | P | 23.111 | New York Yankees | Tampa (A+) | DL-7 Injured |
| Joely Rodriguez | P | 21.290 | Pittsburgh Pirates | Bradenton (A+) | DL-7 Injured |
| Oscar Hernandez | C | 20.052 | Tampa Bay Rays | Bowling Green (A) | DL-7 Injured |
| Tayler Scott | P | 21.090 | Chicago Cubs | Kane County (A) | DL-7 Injured |
| Mark Appel | P | 22.046 | Houston Astros | Quad Cities (A) | Placed on temporarily inactive list |
| Josh Richardson | P | 22.029 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Jorge Rivero | 2B | 24.236 | New York Mets | Savannah (A) | DL-7 Left thumb contusion |
| Cam Gallagher | C | 20.267 | Kansas City Royals | Lexington (A) | DL-7 Injured |
| Ben Waldrip | 1B | 23.064 | Colorado Rockies | Asheville (A) | Activated from temporarily inactive list |
| Harmen Sidhu | P | 23.019 | Tampa Bay Rays | Hudson Valley (A-) | DL-7 Injured |
| Garrett Custons | C-OF | 27.??? | Toronto Blue Jays | Bluefield (Rk) | Placed on military leave list |
| Nick Parent | C | 23.031 | Chicago White Sox | Bristol (Rk) | Placed on restricted list |
| Matt Oye | P | 27.186 | Los Angeles Angels | Arkansas (AA) | Activated from DL |
| Daniel Schlereth | P | 27.113 | Baltimore Orioles | Norfolk (AAA) | Activated from DL |
| Mike Demark | P | 30.102 | Oakland Athletics | Midland (AA) | Activated from DL |
| Adron Chambers | lf-rf | 26.326 | St. Louis Cardinals | Memphis (AAA) | Activated from DL |
| Wendell Soto | SS | 21.111 | Los Angeles Angels | Burlington (A) | Activated from DL |
| Cael Brockmeyer | C-1B | 21.327 | Chicago Cubs | Boise (A-) | Activated from DL |
| Gabriel Ynoa | P | 20.096 | New York Mets | Savannah (A) | Activated from DL |
| Bryan Rodriguez | P | 22.055 | San Diego Padres | Fort Wayne (A) | Activated from DL |
| Mike Morse | rf-lf | 31.161 | Baltimore Orioles | Baltimore Orioles (MLB) | Traded from Mariners to Orioles for Xavier Avery |
| Scott Barnes | RP | 25.360 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from minors and placed on 60-day DL |
| Jason Kubel | lf | 31.097 | Cleveland Indians | Cleveland Indians (MLB) | Traded from Diamondbacks to Indians for future considerations (Matt Langwell) |
| Samuel Deduno | SP | 30.059 | Minnesota Twins | Minnesota Twins (MLB) | DL-15 Right shoulder soreness |
| Pedro Hernandez | SP | 24.140 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from New Britain (AA) |
| Darin Mastroianni | RF | 28.004 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Wilkin Ramirez | rf-lf | 27.309 | Minnesota Twins | Minnesota Twins (MLB) | DL-15 Fractured left tibia [Fouled pitch off his leg] |
| Xavier Avery | cf | 23.241 | Seattle Mariners | Tacoma (AAA) | Traded from Orioles to Mariners for Michael Morse |
| Alfredo Figaro | RP | 29.054 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Nashville (AAA) |
| John Axford | RP | 30.151 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Traded from Brewers to Cardinals for PTNBL (Mike Blazek) |
| Joseph Ortiz | RP | 23.017 | Texas Rangers | Texas Rangers (MLB) | Recalled from Round Rock (AAA) |
| Ross Wolf | RP | 30.316 | Texas Rangers | Round Rock (AAA) | Optioned to Round Rock (AAA) |
| Abraham Almonte | CF | 24.070 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from Tacoma (AAA) |
| Erasmo Ramirez | SP | 23.120 | Seattle Mariners | Tacoma (AAA) | Optioned to Tacoma (AAA) |
| Taijuan Walker | P | 21.017 | Seattle Mariners | Seattle Mariners (MLB) | Contract purchased from Tacoma (AAA) |
| Brandon Gomes | RP | 29.046 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Recalled from Durham (AAA) |
| Jake Odorizzi | SP | 23.156 | Tampa Bay Rays | Durham (AAA) | Optioned to Durham (AAA) |
| Nick Christiani | RP | 26.044 | Cincinnati Reds | Louisville (AAA) | Optioned to Louisville (AAA) |
| Zach Duke | RP | 30.133 | Cincinnati Reds | Cincinnati Reds (MLB) | Contract purchased from Louisville (AAA) |
| Justin Freeman | P | 26.312 | Cincinnati Reds | Louisville (AAA) | Designated for Assignment |
| Edinson Volquez | SP | 30.058 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed to 1-year contract for 2013-2013 ($0m) |
| Chris Withrow | RP | 24.151 | Los Angeles Dodgers | Albuquerque (AAA) | Optioned to Albuquerque (AAA) |
| Kelly Shoppach | c | 33.123 | Cleveland Indians | Columbus (AAA) | Signed to minor league contract |
| James Jones | RF | 24.340 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Jimmy Van Ostrand | LF | 29.023 | Washington Nationals | Syracuse (AAA) | Assigned to Syracuse (AAA) |
| John Ruettiger | CF | 23.343 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Chris Schaeffer | C | 25.285 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Tony Sanchez | c | 25.102 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Jimmy Rider | IF. | 23.113 | Pittsburgh Pirates | West Virginia (A) | Assigned to West Virginia (A) |
| Chase Anselment | C-OF | 22.319 | Atlanta Braves | Lynchburg (A+) | Assigned to Lynchburg (A+) |
| Jack Cleary | C | 23.071 | Milwaukee Brewers | Helena (Rk) | Assigned to Helena (Rk) |
| Reymond Nunez | 1B | 22.339 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Chance Ross | IF | 23.183 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Jonathan Keener | C | 23.263 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Ydarqui Marte | LF | 20.324 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Yonathan Mejia | 2B | 20.345 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Robert Ramirez | 3B | 21.042 | Cincinnati Reds | Clinton (A) | Assigned to Clinton (A) |
| Emilio Guerrero | SS | 21.009 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Alberti Chavez | | 18.040 | Cincinnati Reds | Bakersfield (A+) | Assigned to Bakersfield (A+) |
| Kevin Garcia | | 20.072 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Luis Reynoso | | 18.362 | Houston Astros | Greeneville (Rk) | Assigned to Greeneville (Rk) |
| Frank Francisco | RP | 33.080 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) for rehab |
| Dustin McGowan | RP | 31.159 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) for rehab |
| Sheldon McDonald | P | 24.298 | Chicago Cubs | Daytona (A+) | Assigned to Daytona (A+) |
| Steven Delabar | RP | 30.044 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) for rehab |
| Nick Hill | P | 28.212 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Preston Claiborne | RP | 25.222 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Tyler LaTorre | C | 30.130 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) |
| Jeff Beliveau | P | 26.225 | Tampa Bay Rays | Montgomery (AA) | Assigned to Montgomery (AA) |
| Richard Castillo | P | 23.323 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Tim Melville | P | 23.325 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Kenny Socorro | P | 24.089 | Chicago Cubs | Kane County (A) | |
| J.D. Osborne | P | 22.290 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Corey Williams | P | 23.057 | Minnesota Twins | New Britain (AA) | Assigned to New Britain (AA) |
| Francisco Jimenez | P | 24.332 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Casey Sadler | P | 23.048 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| T.J. Oakes | P | 23.046 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Garrett Cortright | P | 21.333 | Baltimore Orioles | Aberdeen (A-) | Assigned to Aberdeen (A-) |
| Charles Basford | P | 23.045 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Daniel Norris | P | 20.127 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Jose Almarante | P | 24.315 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Brady Lail | P | 20.021 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Reymin Guduan | | 21.167 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Luis Cabrera | | 23.016 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Nataniel Rodriguez | | 23.003 | Los Angeles Angels | Orem (Rk) | Assigned to Orem (Rk) |
| Ronald Herrera | | 18.119 | Oakland Athletics | Vermont (A-) | Assigned to Vermont (A-) |
| Dallas Martinez | P | 18.306 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Miguel Gonzalez | P | 26.341 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Signed to 3-year contract for 2014-2016 ($15m) out of Cuba |
| Chase Boruff | P | 25.034 | | | Released by Royals |
| Hein Robb | P | 21.110 | | | Released by Twins |
| Pat Stover | OF | 22.352 | | | Released by Dodgers |
| Alan Abreu | IF | 23.077 | | | Released by Astros |
| Niko Spezial | P | 22.302 | | | Released by Nationals |
| Jordan Elliott | P | 23.264 | | | Released by Phillies |
| Ryan Walker | IF | 21.157 | Minnesota Twins | Gulf Coast Twins (Rk) | Assigned to GCL Twins (Rk) |
