| Thad Weber | RP | 28.320 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Blake Davis | SS | 29.236 | Milwaukee Brewers | Nashville (AAA) | DL-7 Injured |
| Chase Lambin | 2B | 34.038 | Kansas City Royals | Omaha (AAA) | DL-7 Right thigh contusion |
| Kevin Kouzmanoff | 3B | 32.020 | Miami Marlins | New Orleans (AAA) | DL-7 left trapezius trigger points |
| David Ross | c | 36.148 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) for rehab |
| Slade Heathcott | CF | 22.320 | New York Yankees | Trenton (AA) | DL-7 Right knee tendinopathy |
| Christian Walker | 3B | 22.139 | Baltimore Orioles | Bowie (AA) | DL-7 Injured |
| Jonathan Pettibone | SP | 23.026 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) for rehab |
| Josh Romanski | P | 26.300 | | | Released by White Sox |
| Alex McClure | SS | 24.059 | | | Announced retirement |
| Donald Lutz | lf | 24.189 | Cincinnati Reds | Pensacola (AA) | DL-7 Fractured finger |
| Lance Berkman | dh | 37.186 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) for rehab |
| Ryan Mount | OF | 26.362 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Brandon Efferson | P | 24.262 | Los Angeles Angels | Inland Empire (A+) | DL-7 Right arm soreness |
| Taiwan Easterling | CF | 24.171 | Chicago Cubs | Daytona (A+) | DL-7 Injured |
| Casey Lawrence | P | 25.291 | Toronto Blue Jays | Dunedin (A+) | Activated from DL |
| Shawn Griffith | P | 26.082 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Seth Streich | P | 22.176 | Oakland Athletics | Beloit (A) | DL-7 Injured |
| Jose Berrios | P | 19.079 | Minnesota Twins | Cedar Rapids (A) | DL-7 Injured |
| Edward Concepcion | P | 24.315 | San Francisco Giants | Augusta (A) | DL-7 Injured |
| Tim Brechbuehler | P | 23.297 | Toronto Blue Jays | Vancouver (A-) | DL-7 Injured |
| Andrew Ferreira | P | 22.296 | Minnesota Twins | Elizabethton (Rk) | DL-7 Injured |
| Kenn Kasparek | P | 27.325 | Pittsburgh Pirates | Altoona (AA) | Activated from DL |
| Jimmy Gallagher | 1B | 27.345 | Chicago White Sox | Charlotte (AAA) | Activated from DL |
| Angel Villalona | IF | 23.001 | San Francisco Giants | Richmond (AA) | Activated from DL |
| Pete Hissey | CF | 23.209 | Boston Red Sox | Portland (AA) | Activated from DL |
| Dan Barnes | P | 23.297 | Toronto Blue Jays | Dunedin (A+) | Activated from DL |
| Jonathan Galvez | 2B | 22.208 | San Diego Padres | Tucson (AAA) | Activated from DL |
| Jio Mier | SS | 22.353 | Houston Astros | Corpus Christi (AA) | Activated from DL |
| Emilio Bonifacio | 2b | 28.113 | Kansas City Royals | Kansas City Royals (MLB) | Traded from Blue Jays to Royals for future considerations |
| Miguel Tejada | 2b | 39.081 | Kansas City Royals | Kansas City Royals (MLB) | Transferred to 60-day DL |
| Travis Blackley | RP | 30.283 | Texas Rangers | Round Rock (AAA) | Traded from Astros to Rangers |
| Munenori Kawasaki | 2b | 32.072 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Kevin Pillar | lf | 24.222 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from Buffalo (AAA) |
| Colby Rasmus | cf | 27.003 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Left oblique strain |
| Marwin Gonzalez | ss | 24.153 | Houston Astros | Houston Astros (MLB) | Recalled from Oklahoma City (AAA) |
| Tony Campana | cf | 27.076 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Recalled from Reno (AAA) |
| Tyler Skaggs | SP | 22.032 | Arizona Diamondbacks | Reno (AAA) | Optioned to Reno (AAA) |
| Delmon Young | rf | 27.334 | | | Released by Phillies |
| Steven Ames | RP | 25.152 | Miami Marlins | New Orleans (AAA) | Optioned to New Orleans (AAA) |
| Nick Maronde | RP | 23.343 | Los Angeles Angels | Salt Lake (AAA) | Optioned to Salt Lake (AAA) |
| Andrew Romine | 2b | 27.233 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Jeremy Hefner | SP | 27.156 | New York Mets | Las Vegas (AAA) | Optioned to Las Vegas (AAA) |
| Jeremy Hefner | SP | 27.156 | New York Mets | New York Mets (MLB) | DL-15 Partially torn right MCL |
| Ronny Paulino | C | 32.115 | Detroit Tigers | Toledo (AAA) | Traded from Orioles to Tigers for cash |
| Jorge De Leon | RP | 25.365 | Houston Astros | Oklahoma City (AAA) | Optioned to Oklahoma City (AAA) |
| Lew Ford | CF-RF | 37.002 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Michael Earley | LF | 25.152 | Chicago White Sox | Charlotte (AAA) | Assigned to Charlotte (AAA) |
| Josh Fellhauer | LF | 25.143 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Greg Golson | RF-CF | 27.331 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Miguel Abreu | SS-3B | 28.273 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) for rehab |
| Zach Zaneski | C | 27.048 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Adam Heisler | CF | 25.068 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Jake Smolinski | LF | 24.186 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) |
| Ronald Bermudez | RF-CF | 25.069 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Ben Kline | IF | 24.255 | Tampa Bay Rays | Hudson Valley (A-) | Assigned to Hudson Valley (A-) |
| Trent Mummey | CF | 24.221 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Lee Orr | RF | 24.295 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Joash Brodin | OF-IF | 26.143 | Arizona Diamondbacks | Visalia (A+) | Contract purchased from Long Island (Atlantic) |
| Luis Jimenez | 3b | 25.209 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Tyler Naquin | OF | 22.112 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Taylor Motter | 3B-SS | 23.330 | Tampa Bay Rays | Charlotte (A+) | Assigned to Charlotte (A+) |
| Brad Zapenas | 3B | 23.249 | Chicago Cubs | Kane County (A) | Assigned to Kane County (A) |
| Matt Wessinger | IF | 22.328 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Zach Osborne | IF | 23.116 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Hernan Perez | 2b | 22.141 | Detroit Tigers | Toledo (AAA) | Assigned to Toledo (AAA) |
| Adolfo Reina | C | 23.204 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Leonel Escobar | C | 22.344 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Kris Bryant | 3B | 21.223 | Chicago Cubs | Daytona (A+) | Assigned to Daytona (A+) |
| Sean Coyle | 2B | 21.210 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Cito Culver | SS | 20.353 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Brock Hebert | IF | 22.095 | Seattle Mariners | Clinton (A) | Assigned to Clinton (A) |
| Logan Vick | IF-OF | 22.296 | Cleveland Indians | Carolina (A+) | Assigned to Carolina (A+) |
| Heiker Meneses | SS-2B | 22.044 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Matty Johnson | LF-RF | 25.126 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Cael Brockmeyer | C-1B | 21.311 | Chicago Cubs | Boise (A-) | Assigned to Boise (A-) |
| Dan Vogelbach | 1B | 20.240 | Chicago Cubs | Daytona (A+) | Assigned to Daytona (A+) |
| Nic Cuckovich | 3B | 21.311 | Kansas City Royals | Burlington (Rk) | Assigned to Burlington (Rk) |
| Alex San Juan | C | 22.106 | Colorado Rockies | Tri-City (A-) | Signed as undrafted free agent out of college |
| Ketel Marte | | 19.306 | Seattle Mariners | High Desert (A+) | Assigned to High Desert (A+) |
| Herlis Rodriguez | | 19.065 | Philadelphia Phillies | Williamsport (A-) | Assigned to Williamsport (A-) |
| Mauricio Ramos | SS | 21.194 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Calten Daal | SS | 20.013 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Abiatal Avelino | SS | 18.181 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Jamie Westbrook | SS | 18.057 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Justin Williams | SS | 17.360 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Rando Moreno | | 21.069 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Octavio Dotel | RP | 37.263 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) for rehab |
| Carlos Hernandez | P | 26.163 | Oakland Athletics | Sacramento (AAA) | Assigned to Sacramento (AAA) |
| Kyle Drabek | P | 25.250 | Toronto Blue Jays | Buffalo (AAA) | Assigned to Buffalo (AAA) |
| Tyler LaTorre | C | 30.114 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) |
| Cole Cook | P | 24.300 | Cleveland Indians | Carolina (A+) | Assigned to Carolina (A+) |
| Blayne Weller | P | 23.196 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Patrick Urckfitz | P | 25.024 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Joe Van Meter | P | 24.300 | Tampa Bay Rays | Montgomery (AA) | Signed to minor league contract |
| Dallas Tarleton | C | 26.009 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Zac Rosscup | P | 25.066 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| David Putman | P | 23.167 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Blake Treinen | P | 25.045 | Washington Nationals | Auburn (A-) | Assigned to Auburn (A-) |
| Jordan Elliott | P | 23.248 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Contract purchased from Washington (Frontier) |
| Tony Bryant | P | 22.118 | Colorado Rockies | Tri-City (A-) | Signed as undrafted free agent out of college |
| Cody Forsythe | P | 22.331 | Philadelphia Phillies | Clearwater (A+) | Assigned to Clearwater (A+) |
| Carlos Vazquez | P | 21.346 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Jimmie Sherfy | P | 21.231 | Arizona Diamondbacks | South Bend (A) | Assigned to South Bend (A) |
| Charles Basford | P | 23.029 | New York Yankees | Staten Island (A-) | Assigned to Staten Island (A-) |
| Jose Jose | | 23.024 | Arizona Diamondbacks | Hillsboro (A-) | Assigned to Hillsboro (A-) |
| Miguel Sulbaran | | 19.148 | Minnesota Twins | Cedar Rapids (A) | Traded from Dodgers to Twins as PTNBL for Drew Butera |
| Pat Goetze | P | 19.164 | Boston Red Sox | Gulf Coast Red Sox (Rk) | |
| Jalen Williams | P | 18.115 | Boston Red Sox | Gulf Coast Red Sox (Rk) | |
| Carlos Gomez | P | 21.137 | New York Mets | Kingsport (Rk) | |
| Luis Santos | P | 22.184 | Kansas City Royals | Idaho Falls (Rk) | Assigned to Idaho Falls (Rk) |
| Kyle Grana | P | 22.110 | St. Louis Cardinals | Johnson City (Rk) | Assigned to Johnson City (Rk) |
| Chris Motta | P | 23.145 | Philadelphia Phillies | Gulf Coast Phillies (Rk) | Assigned to GCL Phillies (Rk) |
| Stefan Sabol | C | 21.194 | New York Mets | Savannah (A) | Activated from DL |
