| Ryan Madson | P | 32.343 | Los Angeles Angels | Los Angeles Angels (MLB) | Activated from DL |
| Ryan Madson | P | 32.343 | | | Released by Angels |
| Jason Bourgeois | lf | 31.214 | Tampa Bay Rays | Tampa Bay Rays (MLB) | Contract purchased from Durham (AAA) |
| Desmond Jennings | cf | 26.280 | Tampa Bay Rays | Tampa Bay Rays (MLB) | DL-15 Fractured left middle finger [Sliding] |
| Tom Wilhelmsen | RP | 29.234 | Seattle Mariners | Tacoma (AAA) | Optioned to Tacoma (AAA) |
| Barret Loux | P | 24.122 | Chicago Cubs | Iowa (AAA) | DL-7 Right shoulder strain |
| Trent Oeltjen | RF | 30.159 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Fractured nose |
| Mike Ekstrom | P | 29.342 | | | Released by Angels |
| Mauro Gomez | 1b | 28.333 | Toronto Blue Jays | Buffalo (AAA) | DL-7 Injured |
| Antoan Richardson | CF | 29.303 | Minnesota Twins | Rochester (AAA) | DL-7 Injured |
| Cesar Puello | CF-RF | 22.127 | New York Mets | Binghamton (AA) | Suspended for 50 games for violating MLB drug program |
| Luis Sierra | C | 26.014 | Chicago White Sox | Birmingham (AA) | DL-7 Injured |
| Shawn Zarraga | C | 24.197 | Milwaukee Brewers | Huntsville (AA) | DL-7 Injured |
| Terrell Joyce | OF | 21.069 | Houston Astros | Quad Cities (A) | Placed on temporary inactive list |
| Maxx Tissenbaum | 2B | 22.012 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Juri Perez | P | 22.363 | | | Released by Astros |
| Keon Barnum | 1B | 20.202 | Chicago White Sox | Kannapolis (A) | DL-7 Injured |
| Elias Pinales | P | 20.272 | Baltimore Orioles | Gulf Coast Orioles (Rk) | DL-60 Injured [-] |
| Yeison Hernandez | SS | 21.038 | | | Released by Marlins |
| Jared Mitchell | CF | 24.297 | Chicago White Sox | Birmingham (AA) | Activated from DL |
| Matt Koch | C | 24.258 | Minnesota Twins | Fort Myers (A+) | Activated from DL |
| Damien Magnifico | P | 22.074 | Milwaukee Brewers | Brevard County (A+) | Activated from DL |
| Jose Nivar | P | 24.159 | Baltimore Orioles | Delmarva (A) | Activated from DL |
| J.A. Happ | SP | 30.291 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Activated from DL |
| Michael Schwimer | P | 27.168 | Toronto Blue Jays | Buffalo (AAA) | Designated for Assignment |
| Carter Capps | RP | 22.364 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Eduardo Sanchez | RP | 24.171 | Chicago Cubs | Iowa (AAA) | Optioned to Iowa (AAA) |
| Xavier Cedeno | RP | 26.345 | Washington Nationals | Syracuse (AAA) | Optioned to Syracuse (AAA) |
| Tanner Roark | RP | 26.305 | Washington Nationals | Washington Nationals (MLB) | Contract purchased from Syracuse (AAA) |
| Ross Detwiler | SP | 27.153 | Washington Nationals | Washington Nationals (MLB) | Transferred to 60-day DL |
| Wilmer Flores | 3b | 22.000 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| Cesar Jimenez | RP | 28.267 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from Lehigh Valley (AAA) |
| Jason Bay | rf | 34.320 | | | Released by Mariners |
| Julio Borbon | lf | 27.167 | Chicago Cubs | Iowa (AAA) | Outrighted to Iowa (AAA) |
| Bobby Parnell | RP | 28.332 | New York Mets | New York Mets (MLB) | DL-15 Neck stiffness [-] |
| Domonic Brown | lf | 25.338 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Activated from DL |
| Laynce Nix | rf | 32.280 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Designated for Assignment |
| Ronny Cedeno | ss | 30.185 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from Lake Elsinore (A+) |
| Ted Lilly | SP | 37.215 | San Francisco Giants | San Francisco Giants (MLB) | Signed to Minor League Contract |
| Brian Roberts | 2b | 35.301 | Baltimore Orioles | Baltimore Orioles (MLB) | Reinstated from Paternity Leave list |
| Dewayne Wise | cf | 35.163 | | | Released by White Sox |
| Grant Green | 2b | 25.314 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| Daniel Stange | RP | 27.227 | Los Angeles Angels | Salt Lake (AAA) | Optioned to Salt Lake (AAA) |
| Corey Kluber | SP | 27.118 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Sprained finger on right hand [-] |
| Matt Langwell | RP | 27.092 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Jon Niese | SP | 26.283 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) for rehab |
| Wilson Betemit | dh | 31.277 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) for rehab |
| Andy Marte | 3B | 29.259 | Los Angeles Angels | Salt Lake (AAA) | Signed to Minor League Contract |
| Micah Owings | 1B | 30.312 | Milwaukee Brewers | Huntsville (AA) | Assigned to Huntsville (AA) |
| Anderson De La Rosa | C | 29.005 | Milwaukee Brewers | Huntsville (AA) | Assigned to Huntsville (AA) |
| Griff Erickson | C | 25.148 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Cory Vaughn | RF | 24.097 | New York Mets | Binghamton (AA) | Assigned to Binghamton (AA) |
| Tony Caldwell | C | 24.247 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Matt Duffy | 3B | 24.181 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Austin Barnes | C | 23.221 | Miami Marlins | Jacksonville (AA) | Assigned to Jacksonville (AA) |
| Dan Gulbransen | OF | 22.213 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Tom Murphy | C | 22.125 | Colorado Rockies | Tulsa (AA) | Assigned to Tulsa (AA) |
| Tyler White | IF | 22.281 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Cael Brockmeyer | C-1B | 21.303 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Saxon Butler | P | 23.087 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Justin Bianco | CF | 20.347 | Arizona Diamondbacks | Missoula (Rk) | Assigned to Missoula (Rk) |
| Ramon Torres | | 20.196 | Kansas City Royals | Lexington (A) | Assigned to Lexington (A) |
| Juan Herrera | 2B | 20.039 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Jose Briceno | C | 20.321 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Daniel Castro | 2B-SS | 20.265 | Atlanta Braves | Lynchburg (A+) | |
| Reynaldo Bruguera | | 21.275 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Victor Reyes | | 18.305 | Atlanta Braves | Danville (Rk) | Assigned to Danville (Rk) |
| Chad Jenkins | SP | 25.228 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Daniel McCutchen | P | 30.314 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Blake Johnson | P | 28.053 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Jason Urquidez | P | 30.328 | Los Angeles Angels | Salt Lake (AAA) | Contract purchased from Lancaster (Atlantic) |
| Justin Souza | P | 27.288 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Matt Summers | P | 23.354 | Minnesota Twins | New Britain (AA) | Assigned to New Britain (AA) |
| Jordan Jankowski | C | 24.081 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Christopher Beck | P | 22.336 | Chicago White Sox | Winston-Salem (A+) | |
| Zack Dodson | P | 23.014 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Geoffrey Davenport | P | 23.145 | Cleveland Indians | Arizona Indians (Rk) | Assigned to Arizona Indians (Rk) |
| Diego Moreno | P | 26.016 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Ralston Cash | P | 21.352 | Los Angeles Dodgers | Arizona Dodgers (Rk) | Assigned to Arizona Dodgers (Rk) |
| Danny Winkler | P | 23.185 | Colorado Rockies | Tulsa (AA) | Assigned to Tulsa (AA) |
| Jerad Eickhoff | P | 23.035 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Keith Couch | P | 23.274 | Boston Red Sox | Pawtucket (AAA) | Assigned to Pawtucket (AAA) |
| Pat Christensen | P | 22.222 | Houston Astros | Quad Cities (A) | Assigned to Quad Cities (A) |
| Shae Simmons | P | 22.337 | Atlanta Braves | Mississippi (AA) | Assigned to Mississippi (AA) |
| Andrew Russell | P | 29.101 | Atlanta Braves | Gwinnett (AAA) | Assigned to Gwinnett (AAA) |
| Michael Zouzalik | P | 23.024 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Tim Peterson | P | 22.165 | New York Mets | Savannah (A) | Assigned to Savannah (A) |
| Jacob Newberry | | 22.300 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Tyler Brunnemann | P | 21.363 | Houston Astros | Tri City (A-) | Assigned to Tri City (A-) |
| Seth Wagner | P | 18.222 | Minnesota Twins | Gulf Coast Twins (Rk) | |
| Arismendy Ozoria | P | 22.364 | Los Angeles Dodgers | Rancho Cucamonga (A+) | DL-7 Injured |
| Nick Martinez | P | 23.001 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Danny Valencia | dh | 28.321 | Baltimore Orioles | Norfolk (AAA) | Optioned to Norfolk (AAA) |
| Nick Mutz | P | 23.052 | | | Signed by New Jersey (CanAm) |
| Juan Ciriaco | SS-LF | 29.357 | San Francisco Giants | Richmond (AA) | Activated from DL |
