| Oswaldo Arcia | rf-lf | 22.085 | Minnesota Twins | Minnesota Twins (MLB) | Recalled from Rochester (AAA) |
| Melky Cabrera | lf | 28.356 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Left knee strain [Attempting to throw ball back in to IF cutoff man] |
| Neil Wagner | RP | 29.214 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Recalled from Buffalo (AAA) |
| Carlos Pena | dh | 35.077 | | | Released by Astros |
| Elian Herrera | lf | 28.182 | Los Angeles Dodgers | Albuquerque (AAA) | Optioned to Albuquerque (AAA) |
| Scott Van Slyke | RF-1B | 27.009 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Albuquerque (AAA) |
| Robert Andino | 3b | 29.099 | Pittsburgh Pirates | Indianapolis (AAA) | Traded from Mariners to Pirates for future considerations |
| Luis Rodriguez | 2B | 33.036 | Los Angeles Angels | Salt Lake (AAA) | DL-7 Strained left thumb |
| Ryan Rodebaugh | P | 24.125 | Texas Rangers | Round Rock (AAA) | DL-7 Injured |
| Brett Lorin | P | 26.124 | Arizona Diamondbacks | Reno (AAA) | DL-7 Injured |
| Mitch Maier | RF | 31.033 | Boston Red Sox | Pawtucket (AAA) | Activated from DL |
| Jess Todd | P | 27.104 | Detroit Tigers | Toledo (AAA) | Activated from DL |
| Jackie Bradley | CF | 23.105 | Boston Red Sox | Pawtucket (AAA) | DL-7 Injured |
| Matt Hoffman | P | 24.257 | Detroit Tigers | Toledo (AAA) | DL-7 Injured |
| Angel Sanchez | SS | 29.317 | | | Released by White Sox |
| Fred Lewis | P | 26.229 | New York Yankees | Trenton (AA) | DL-7 Injured |
| Mike Dennhardt | P | 23.062 | Cincinnati Reds | Bakersfield (A+) | DL-7 Injured |
| Matt Scioscia | C-1B | 24.316 | Los Angeles Angels | Burlington (A) | Activated from DL |
| Matt Smith | P | 25.233 | | | Released by Marlins |
| Anthony Santander | OF | 18.287 | Cleveland Indians | Lake County (A) | DL-7 Injured |
| Brent Peterson | SS | 20.286 | Cincinnati Reds | Clinton (A) | DL-7 Injured |
| Cole Nelson | P | 24.019 | Atlanta Braves | Rome (A) | DL-7 Injured |
| Aaron Gates | P | 23.112 | New York Yankees | Charleston (sc) (A) | Activated from DL |
| Brandon Love | P | 23.149 | Los Angeles Angels | Burlington (A) | Activated from DL |
| Kelvin De Leon | RF | 22.277 | New York Yankees | Charleston (sc) (A) | Activated from DL |
| Gregory Pron | RF | 24.211 | New York Mets | Savannah (A) | Activated from DL |
| Jesus Galindo | CF | 22.344 | San Francisco Giants | Augusta (A) | Activated from DL |
| Shayne Houck | OF | 23.065 | San Francisco Giants | Augusta (A) | Activated from DL |
| Adam Rosales | ss | 30.074 | Texas Rangers | Texas Rangers (MLB) | Claimed off waivers from Athletics by Rangers |
| Ethan Martin | SP | 24.057 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Jeremy Horst | RP | 27.305 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Recalled from Lehigh Valley (AAA) |
| Zach Miner | RP | 31.143 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Contract purchased from Lehigh Valley (AAA) |
| Jonathan Pettibone | SP | 23.014 | Philadelphia Phillies | Philadelphia Phillies (MLB) | DL-15 Strained right shoulder [Felt discomfort for 3 starts] |
| J.C. Ramirez | RP | 24.351 | Philadelphia Phillies | Philadelphia Phillies (MLB) | Designated for Assignment |
| Vic Black | RP | 25.071 | Pittsburgh Pirates | Indianapolis (AAA) | Optioned to Indianapolis (AAA) |
| Jared Hughes | RP | 28.029 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Activated from DL |
| Hernan Perez | 2b | 22.129 | Detroit Tigers | Erie (AA) | Optioned to Erie (AA) |
| Josh Edgin | RP | 26.228 | New York Mets | New York Mets (MLB) | DL-15 Ribcage stress fracture [Pain increased since before all-star break] |
| Pedro Feliciano | RP | 36.342 | New York Mets | New York Mets (MLB) | Contract purchased from Las Vegas (AAA) |
| Boof Bonser | P | 31.292 | | | Released by Indians |
| Cesar Carrillo | P | 29.095 | | | Released by Tigers |
| Steve Johnson | RP | 25.337 | Baltimore Orioles | Baltimore Orioles (MLB) | Activated from DL |
| Brian Roberts | 2b | 35.297 | Baltimore Orioles | Baltimore Orioles (MLB) | Placed on Paternity Leave list |
| Curtis Granderson | dh-lf | 32.139 | New York Yankees | New York Yankees (MLB) | Activated from DL |
| Melky Mesa | rf | 26.183 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Optioned to Scranton/Wilkes-Barre (AAA) |
| Thomas Neal | dh-rf | 25.351 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Designated for Assignment |
| Engel Beltre | lf | 23.274 | Texas Rangers | Round Rock (AAA) | Optioned to Round Rock (AAA) |
| Steve Clevenger | 3b | 27.119 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Joe Dunigan | LF-1B | 27.126 | Seattle Mariners | Tacoma (AAA) | Assigned to Tacoma (AAA) |
| Darin Mastroianni | cf | 27.341 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) for rehab |
| Buck Britton | 3B-2B | 27.078 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Kevin Torres | 1B-C | 23.159 | Texas Rangers | Hickory (A) | Assigned to Hickory (A) |
| Adam Matthews | OF | 23.114 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Brandon Miller | C | 23.298 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Matt Snyder | IF | 23.046 | New York Yankees | Tampa (A+) | Assigned to Tampa (A+) |
| Billy Burns | CF | 23.337 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Jake Brown | IF | 23.168 | Chicago White Sox | Bristol (Rk) | Assigned to Bristol (Rk) |
| J.R. Reynolds | C | 23.002 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| John Cannon | C | 23.083 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Daniel Torres | C | 21.065 | Seattle Mariners | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| George Barber | OF | 23.359 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Brock Hebert | IF | 22.083 | Seattle Mariners | High Desert (A+) | Assigned to High Desert (A+) |
| Matty Johnson | LF-RF | 25.114 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Rougned Odor | 2B | 19.180 | Texas Rangers | Frisco (AA) | Assigned to Frisco (AA) |
| Humberto Valor | SS | 20.327 | Cincinnati Reds | Clinton (A) | Assigned to Clinton (A) |
| Matt Duffy | IF | 22.199 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Jerison Lopez | | 21.344 | New York Yankees | Gulf Coast Yankees (Rk) | Assigned to Gulf Coast Yankees (Rk) |
| Rehiner Cordova | | 19.203 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Miguel Del Castillo | | 21.293 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Byron Capellan | | 19.358 | Baltimore Orioles | Gulf Coast Orioles (Rk) | Assigned to Gulf Coast Orioles (Rk) |
| Byron Capellan | | 19.358 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Chad Beck | P | 28.197 | Toronto Blue Jays | Gulf Coast Blue Jays (Rk) | Assigned to Gulf Coast Blue Jays (Rk) |
| Dan Sattler | P | 29.265 | Minnesota Twins | New Britain (AA) | Assigned to New Britain (AA) |
| Marco Estrada | SP | 30.028 | Milwaukee Brewers | Nashville (AAA) | Assigned to Nashville (AAA) for rehab |
| Michael Kirkman | RP | 26.318 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) for rehab |
| Jose Lugo | P | 29.114 | Atlanta Braves | Rome (A) | Assigned to Rome (A) |
| Kyle Drabek | P | 25.238 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Fabian Williamson | P | 24.286 | Cincinnati Reds | Bakersfield (A+) | Contract purchased from Laredo (American) |
| Neftali Feliz | P | 25.092 | Texas Rangers | Arizona Rangers (Rk) | Assigned to Arizona Rangers (Rk) for rehab |
| Tom Cochran | P | 30.290 | Philadelphia Phillies | Lehigh Valley (AAA) | Assigned to Lehigh Valley (AAA) |
| Jarret Martin | P | 23.353 | Los Angeles Dodgers | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Matthew Swilley | P | 22.226 | Tampa Bay Rays | Gulf Coast Rays (Rk) | |
| Cal Bowling | P | 23.284 | Chicago White Sox | Bristol (Rk) | Assigned to Bristol (Rk) |
| Mike McCarthy | P | 25.258 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Cody Kendall | P | 23.233 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Ryan Arrowood | IF-P | 22.343 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Manuel Rivera | P | 23.335 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Eduardo Figueroa | P | 24.245 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Jon Gray | P | 21.271 | Colorado Rockies | Modesto (A+) | Assigned to Modesto (A+) |
| Michael Lorenzen | OF | 21.211 | Cincinnati Reds | Bakersfield (A+) | Assigned to Bakersfield (A+) |
| Marco Gonzales | P | 21.168 | St. Louis Cardinals | Palm Beach (A+) | Assigned to Palm Beach (A+) |
| Kramer Sneed | P | 24.299 | Los Angeles Angels | Arizona Angels (Rk) | Assigned to Arizona Angels (Rk) |
| Brody Greer | IF | 22.079 | Chicago Cubs | Arizona Diamondbacks (Rk) | Signed as undrafted free agent out of college |
| Dayan Diaz | P | 24.173 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Andrew Hanse | P | 22.081 | Tampa Bay Rays | Bowling Green (A) | Assigned to Bowling Green (A) |
| Isliexel Gonzalez | | 22.084 | Seattle Mariners | Pulaski (Rk) | Assigned to Pulaski (Rk) |
| Jackson Mateo | | 20.345 | Los Angeles Dodgers | Ogden (Rk) | Assigned to Ogden (Rk) |
| Travis Seabrooke | P | 17.321 | Baltimore Orioles | Gulf Coast Orioles (Rk) | |
| Alex Powers | P | 21.158 | Chicago White Sox | Bristol (Rk) | Assigned to Bristol (Rk) |
| Richard Teasley | P | 22.102 | Tampa Bay Rays | Princeton (Rk) | Assigned to Princeton (Rk) |
| Junior Morillo | | 21.277 | Cincinnati Reds | Billings (Rk) | Assigned to Billings (Rk) |
| Eddie Butler | P | 22.142 | Colorado Rockies | Tulsa (AA) | Assigned to Tulsa (AA) |
| Josh Hader | P | 19.117 | Houston Astros | Quad Cities (A) | Traded from Orioles with LJ Hoes to Astros for Bud Norris |
| Andrew Carpenter | IF | 23.119 | | | Released by Angels |
