| Fernando Martinez | lf | 24.214 | Houston Astros | Oklahoma City (AAA) | Outrighted to Oklahoma City (AAA) |
| Robert Coello | RP | 28.170 | Los Angeles Angels | Los Angeles Angels (MLB) | Contract purchased from Salt Lake (AAA) |
| Scott Cousins | rf-lf | 28.110 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Edgar Gonzalez | RP | 30.078 | | | Refused Minor League Assignment - Declared free agency |
| Steve Johnson | SP | 25.255 | Baltimore Orioles | Norfolk (AAA) | Optioned to Norfolk (AAA) |
| Mike Fiers | RP-SP | 27.331 | Milwaukee Brewers | Milwaukee Brewers (MLB) | Recalled from Brevard County (A+) |
| Tom Gorzelanny | RP | 30.304 | Milwaukee Brewers | Milwaukee Brewers (MLB) | DL-15 Left shoulder tendinitis |
| Charlie Blackmon | rf | 26.315 | Colorado Rockies | Colorado Rockies (MLB) | Recalled from Colorado Springs (AAA) |
| Michael Cuddyer | rf | 34.046 | Colorado Rockies | Colorado Rockies (MLB) | DL-15 Bulging disk in neck |
| Greg Garcia | 2B | 23.277 | St. Louis Cardinals | Memphis (AAA) | DL-7 Injured |
| Brian Sanches | P | 34.277 | Kansas City Royals | Omaha (AAA) | Activated from temporarily inactive list |
| Jeff Mathis | C | 30.042 | Miami Marlins | New Orleans (AAA) | Assigned to New Orleans (AAA) for rehab |
| Travis Buck | RF | 29.176 | San Diego Padres | Tucson (AAA) | DL-7 Injured |
| Sean White | P | 32.017 | Los Angeles Dodgers | Albuquerque (AAA) | DL-7 Strained lat |
| Aaron Cook | P | 34.093 | Colorado Rockies | Colorado Springs (AAA) | DL-7 Inflammation in right elbow |
| Dallas Tarleton | C | 25.281 | Colorado Rockies | Colorado Springs (AAA) | Placed on temporary inactive list |
| Drew Carpenter | P | 27.359 | Colorado Rockies | Colorado Springs (AAA) | Traded from Cubs to Rockies for PTNBL |
| Dan Wheeler | P | 35.153 | | | Released by Royals |
| Ryan Pope | P | 26.356 | | | Released by Yankees |
| Gil Velazquez | SS | 33.208 | | | Released by Yankees |
| Cody Johnson | LF | 24.267 | | | Released by Yankees |
| Luis Durango | CF | 27.019 | | | Released by White Sox |
| Brett Anderson | RP | 25.101 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) for rehab |
| Jenrry Mejia | SP-RP | 23.213 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) for rehab |
| Paul Hoenecke | 3B | 22.308 | Los Angeles Dodgers | Great Lakes (A) | DL-7 Injured |
| Jorge Flores | SS | 21.169 | Toronto Blue Jays | Lansing (A) | DL-7 Injured |
| Boss Moanaroa | 1B | 21.305 | Boston Red Sox | Greenville (A) | DL-7 Injured |
| Chad Zurcher | 2B-SS | 24.260 | New York Mets | Savannah (A) | DL-7 Left wrist sprain |
| Alberto Gonzalez | ss | 30.024 | New York Yankees | New York Yankees (MLB) | Contract purchased from Scranton/Wilkes-Barre (AAA) |
| Eduardo Nunez | ss | 25.332 | New York Yankees | New York Yankees (MLB) | DL-15 Left ribcage strain [-] |
| Mark Teixeira | 1b | 33.031 | New York Yankees | New York Yankees (MLB) | Transferred to 60-day DL |
| Edgar Gonzalez | RP | 30.078 | Houston Astros | Houston Astros (MLB) | Signed to 1-year contract for 2013 ($0m) |
| Philip Humber | SP-RP | 30.142 | Houston Astros | Houston Astros (MLB) | Designated for assignment |
| Greg Burke | RP | 30.233 | New York Mets | New York Mets (MLB) | Recalled from Las Vegas (AAA) |
| David Ross | c | 36.054 | Boston Red Sox | Boston Red Sox (MLB) | DL-7 Concussion |
| John Gast | SP | 24.085 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Contract purchased from Memphis (AAA) |
| Jason Motte | CL | 30.324 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Transferred to 60-day DL |
| Jake Westbrook | SP | 35.225 | St. Louis Cardinals | St. Louis Cardinals (MLB) | DL-15 Right elbow inflammation |
| Drew Sutton | 2B | 29.317 | Boston Red Sox | Pawtucket (AAA) | Activated from DL |
| Tommy Mendonca | 3B | 25.030 | Philadelphia Phillies | Reading (AA) | Contract purchased from Camden (Atlantic) |
| Reegie Corona | 2b | 26.186 | New York Yankees | Scranton/Wilkes-Barre (AAA) | Assigned to Scranton/Wilkes-Barre (AAA) |
| Reegie Corona | 2b | 26.186 | New York Yankees | Trenton (AA) | Assigned to Trenton (AA) |
| Danny Lehmann | C | 27.249 | Minnesota Twins | Rochester (AAA) | Assigned to Rochester (AAA) |
| Niuman Romero | SS | 28.108 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Justin Dalles | C | 24.133 | Philadelphia Phillies | Lakewood (A) | Assigned to Lakewood (A) |
| Travis Tartamella | C | 25.147 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Matt Long | CF-RF | 26.012 | Los Angeles Angels | Salt Lake (AAA) | Assigned to Salt Lake (AAA) |
| Josh Whitaker | RF-LF | 24.093 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Trevor Hairgrove | SS | 23.239 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Cody Stanley | C | 24.142 | St. Louis Cardinals | Springfield (AA) | Assigned to Springfield (AA) |
| Tim Roberson | C | 23.297 | Boston Red Sox | Greenville (A) | Assigned to Greenville (A) |
| Christian Walker | 3B | 22.045 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Richard Stock | C | 22.093 | Cleveland Indians | Lake County (A) | Assigned to Lake County (A) |
| Chris Burke | P-IF | 23.016 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Elevys Gonzalez | 2B-3B | 23.201 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Connor Narron | 3B | 21.182 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Connor Narron | 3B | 21.182 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Anthony Caronia | IF-OF | 21.356 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Robbie Garvey | CF-LF | 24.016 | Los Angeles Dodgers | Great Lakes (A) | Assigned to Great Lakes (A) |
| Vance Albitz | SS | 25.102 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) |
| Chance Ross | IF | 23.073 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Justin Miller | 2B-LF | 24.149 | San Diego Padres | Tucson (AAA) | Assigned to Tucson (AAA) |
| Wilmer Difo | SS | 21.040 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Brett Brach | P | 25.044 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Juan Cedeno | P | 29.267 | Atlanta Braves | Gwinnett (AAA) | Signed to minor league contract |
| Trevor Holder | P | 26.124 | San Diego Padres | Lake Elsinore (A+) | Signed to minor league contract |
| Brian Pearl | P | 24.360 | Cincinnati Reds | Pensacola (AA) | Assigned to Pensacola (AA) |
| Zach Clark | RP | 29.306 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Michael Solbach | P | 27.285 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Brett Hunter | P | 25.320 | Oakland Athletics | Stockton (A+) | Assigned to Stockton (A+) |
| Colby Shreve | P | 25.128 | Philadelphia Phillies | Reading (AA) | Assigned to Reading (AA) |
| Taylor Jordan | P | 24.115 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Zack Thornton | P | 24.358 | Pittsburgh Pirates | Altoona (AA) | Assigned to Altoona (AA) |
| Jose Casilla | P | 23.356 | San Francisco Giants | San Jose (A+) | |
| Kyle Hallock | P | 24.279 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Danny Salazar | P | 23.121 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Pat Lowery | P | 23.040 | Los Angeles Angels | Burlington (A) | Assigned to Burlington (A) |
| Andrew Carpenter | IF | 23.037 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) |
| Ross Stripling | P | 23.170 | Los Angeles Dodgers | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Orangel Arenas | P | 24.042 | Los Angeles Angels | Inland Empire (A+) | Assigned to Inland Empire (A+) |
| Dennis Torres | P | 22.360 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Matt Wisler | P | 20.242 | San Diego Padres | San Antonio (AA) | Assigned to San Antonio (AA) |
| Robert Gsellman | P | 19.298 | New York Mets | Savannah (A) | |
| Dillon Maples | P | 21.003 | Chicago Cubs | Kane County (A) | Assigned to Kane County (A) |
| Silfredo Garcia | | 21.298 | St. Louis Cardinals | Peoria (A) | Assigned to Peoria (A) |
| Bryan Rodriguez | | 21.311 | San Diego Padres | Fort Wayne (A) | Assigned to Fort Wayne (A) |
| Kameron Loe | RP | 31.244 | Atlanta Braves | Gwinnett (AAA) | Signed to minor league contract |
| Shane Opitz | SS | 21.123 | Toronto Blue Jays | Dunedin (A+) | Assigned to Dunedin (A+) |
| Steven Hensley | P | 26.136 | Colorado Rockies | Tulsa (AA) | DL-7 Strained hamstring |
| Lew Ford | CF-RF | 36.273 | Baltimore Orioles | Norfolk (AAA) | DL-7 Injured |
| Michael Fabiaschi | 2B-3B | 24.268 | Oakland Athletics | Midland (AA) | DL-7 Injured |
| Jeurys Familia | RP | 23.214 | New York Mets | New York Mets (MLB) | DL-15 Right biceps tendinitis |
| Chas Mye | P | 25.015 | | | Released by Athletics |
