| Wilson Betemit | dh | 31.162 | Baltimore Orioles | Baltimore Orioles (MLB) | Transferred to 60-day DL |
| Alex Burnett | RP | 25.262 | Baltimore Orioles | Norfolk (AAA) | Claimed off waivers from Blue Jays by Orioles |
| Luis Jimenez | 1b-dh | 25.086 | Los Angeles Angels | Los Angeles Angels (MLB) | Recalled from Salt Lake (AAA) |
| J.B. Shuck | lf | 25.300 | Los Angeles Angels | Salt Lake (AAA) | Optioned to Salt Lake (AAA) |
| Matt Albers | RP | 30.083 | Cleveland Indians | Cleveland Indians (MLB) | Placed on Paternity Leave list |
| Jason Giambi | dh | 42.095 | Cleveland Indians | Cleveland Indians (MLB) | Activated from DL |
| Nick Hagadone | RP | 27.102 | Cleveland Indians | Cleveland Indians (MLB) | Recalled from Columbus (AAA) |
| Corey Kluber | SP | 27.003 | Cleveland Indians | Columbus (AAA) | Optioned to Columbus (AAA) |
| Edgar Gonzalez | RP | 30.049 | Toronto Blue Jays | Buffalo (AAA) | Outrighted to Buffalo (AAA) |
| Jose Reyes | ss | 29.307 | Toronto Blue Jays | Toronto Blue Jays (MLB) | DL-15 Sprained left ankle |
| Cristhian Martinez | RP | 31.038 | Atlanta Braves | Atlanta Braves (MLB) | DL-15 Right shoulder strain |
| Zack Greinke | SP | 29.175 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | DL-15 Broken left collarbone |
| Sean Burroughs | 1B | 32.213 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Signed to minor league contract |
| Shawn Tolleson | RP | 25.085 | Los Angeles Dodgers | Los Angeles Dodgers (MLB) | Recalled from Albuquerque (AAA) |
| Sean Henn | P | 31.355 | New York Mets | New York Mets (MLB) | Signed to minor league contract |
| Chris Leroux | RP | 28.364 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Designated for assignment |
| Bryan Morris | RP | 26.016 | Pittsburgh Pirates | Pittsburgh Pirates (MLB) | Recalled from Indianapolis (AAA) |
| Chase Headley | 3b | 28.339 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) for rehab |
| Carlos Quentin | lf | 30.228 | San Diego Padres | San Diego Padres (MLB) | Suspended for 8 games for charging mound |
| Cody Ransom | 3b | 37.056 | San Diego Padres | San Diego Padres (MLB) | Designated for assignment |
| Thad Weber | P | 28.197 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from Tucson (AAA) |
| Kip Wells | P | 35.357 | Los Angeles Angels | Los Angeles Angels (MLB) | Signed to minor league contract |
| Scott Diamond | SP | 26.257 | Minnesota Twins | Minnesota Twins (MLB) | Activated from DL |
| Liam Hendriks | SP | 24.062 | Minnesota Twins | Rochester (AAA) | Optioned to Rochester (AAA) |
| Yoenis Cespedes | lf | 27.185 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Strained muscle in left hand |
| Michael Taylor | lf | 27.115 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Sacramento (AAA) |
| Munenori Kawasaki | ss | 31.314 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Contract purchased from Buffalo (AAA) |
| Rafael Dolis | RP | 25.094 | Chicago Cubs | Chicago Cubs (MLB) | Recalled from Iowa (AAA) |
| Kyuji Fujikawa | RP | 32.266 | Chicago Cubs | Chicago Cubs (MLB) | DL-15 Strained right forearm |
| Cody Ross | RF | 32.111 | Arizona Diamondbacks | Reno (AAA) | Assigned to Reno (AAA) for rehab |
| Brandon Allen | IF | 27.060 | San Diego Padres | Tucson (AAA) | Signed to minor league contract |
| Tim Torres | LF-RF | 29.153 | Chicago Cubs | Iowa (AAA) | Assigned to Iowa (AAA) |
| Hector Gomez | SS | 25.039 | Milwaukee Brewers | Huntsville (AA) | Assigned to Huntsville (AA) |
| Myles Schroder | C | 25.256 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Brian Harrison | 3B | 24.119 | New York Mets | St. Lucie (A+) | Assigned to St. Lucie (A+) |
| Stephen Branca | SS | 24.003 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Ross Wilson | LF-2B | 24.155 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Creede Simpson | SS | 23.217 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Jason Stolz | SS | 23.023 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Matt Argyropoulos | 3B-1B | 24.232 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Cody Keefer | OF | 22.158 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Joey Rapp | OF | 23.137 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Christian Walker | 3B | 22.016 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Zachary Kirksey | OF | 24.055 | Detroit Tigers | Lakeland (A+) | Assigned to Lakeland (A+) |
| Ben Turner | C-1B | 22.351 | San Francisco Giants | Augusta (A) | |
| Taylor Dugas | OF | 23.119 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Derek Jones | OF | 22.314 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Matt Wessinger | IF | 22.205 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Danny Oh | OF-1B | 23.106 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Cameron Flynn | OF-P | 23.048 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Peter O'Brien | C | 22.272 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Nik Balog | 1B | 23.181 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Kelvin De Leon | RF | 22.166 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Rafael Rodriguez | LF | 20.274 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Jesus Solorzano | CF | 22.248 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Charles Jones | LF | 20.259 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Yordy Cabrera | SS | 22.222 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Viosergy Rosa | 1B | 22.301 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Eric Sim | C | 24.100 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| David Freitas | C | 24.026 | Oakland Athletics | Midland (AA) | Assigned to Midland (AA) |
| Alfredo Lopez | 2B | 23.188 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Torsten Boss | IF | 22.107 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Mitch Delfino | IF | 22.090 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Matt Juengel | IF | 23.090 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Zach Vincej | IF | 21.348 | Cincinnati Reds | Clinton (A) | Assigned to Clinton (A) |
| Kyle Von Tungeln | OF | 22.207 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Tom Murphy | C | 22.010 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Fu-Lin Kuo | 1B | 22.096 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Juancito Martinez | RF | 23.307 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Michael Ramirez | C | 22.351 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Francisco Sosa | LF | 23.045 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Ronald Torreyes | 2B | 20.223 | Chicago Cubs | Tennessee (AA) | Assigned to Tennessee (AA) |
| Anthony Vega | OF | 22.128 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Joel Hutter | SS | 23.044 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Greg Bird | C | 20.155 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Sharif Othman | C | 24.021 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Travious Relaford | SS | 20.335 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Yeicok Calderon | RF | 21.112 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Claudio Custodio | SS | 22.165 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Yeison Hernandez | SS | 20.288 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Pedro Perez | C | 21.341 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Matt Duffy | IF | 22.088 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Rosell Herrera | SS | 20.179 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Roman Hernandez | LF | 25.095 | Kansas City Royals | Northwest Arkansas (AA) | Assigned to Northwest Arkansas (AA) |
| David Dahl | OF | 19.012 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Shayne Houck | OF | 22.319 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Tyler Hollick | OF | 20.209 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Juan Ciriaco | 2B | 22.281 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Eric Marzec | P | 25.091 | Milwaukee Brewers | Huntsville (AA) | Assigned to Huntsville (AA) |
| Frankie Reed | P | 25.061 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Tyson Brummett | P | 28.241 | Toronto Blue Jays | New Hampshire (AA) | Assigned to New Hampshire (AA) |
| Kyle Waldrop | P | 27.168 | Pittsburgh Pirates | Indianapolis (AAA) | Assigned to Indianapolis (AAA) |
| Austin Fleet | P | 25.362 | San Francisco Giants | San Jose (A+) | Assigned to San Jose (A+) |
| Jason Ray | P | 28.273 | San Diego Padres | Tucson (AAA) | Assigned to Tucson (AAA) |
| Caleb Graham | P | 26.085 | Los Angeles Angels | Arkansas (AA) | Assigned to Arkansas (AA) |
| Brian Dupra | P | 24.119 | Washington Nationals | Hagerstown (A) | |
| Richard Bleier | P | 25.363 | Texas Rangers | Round Rock (AAA) | Assigned to Round Rock (AAA) |
| Devin Jones | P | 22.283 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Rayan Gonzalez | P | 22.177 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Miguel Fermin | P | 28.061 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Jesse Meaux | P | 23.248 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Jonathan Vargas | P | 23.319 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Josh Slaats | P | 24.112 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Tom Shirley | P | 24.153 | Houston Astros | Lancaster (A+) | Assigned to Lancaster (A+) |
| Matt Hobgood | P | 22.253 | Baltimore Orioles | Delmarva (A) | |
| Branden Kline | P | 21.197 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Tyler Cravy | P | 23.274 | Milwaukee Brewers | Brevard County (A+) | Assigned to Brevard County (A+) |
| Brady Wager | P | 22.147 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Derek Law | P | 22.211 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Robert Benincasa | P | 22.220 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Taylor Garrison | P | 22.324 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Matt Price | P | 23.217 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Mason McVay | P | 22.241 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Ryan Arrowood | IF-P | 22.232 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Tyler Mizenko | P | 23.004 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Vicente Campos | P | 20.260 | New York Yankees | Charleston (sc) (A) | |
| Carlos Quevedo | P | 23.195 | Houston Astros | Corpus Christi (AA) | Assigned to Corpus Christi (AA) |
| Jose Nivar | P | 24.044 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Mark Blackmar | P | 20.350 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Evan Rutckyj | P | 21.073 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Gabe Encinas | P | 21.114 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Drew Cisco | P | 21.259 | Cincinnati Reds | Clinton (A) | Assigned to Clinton (A) |
| Steven Okert | P | 21.279 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Roberto Padilla | P | 22.288 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Martin Agosta | P | 22.006 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Dietrich Enns | P | 21.333 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Ian Gardeck | P | 22.143 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Brook Hart | P | 24.003 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Drew Steckenrider | OF-P | 22.093 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Chris Stratton | P | 22.234 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Pedro Encarnacion | P | 21.292 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Kendry Flores | P | 21.141 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Jheyson Manzueta | P | 23.129 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Alving Mejias | P | 21.109 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| TJ Oakes | P | 22.272 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Brandon Farley | P | 22.255 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Derek Varnadore | P | 22.277 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Lance Day | P | 23.191 | Houston Astros | Oklahoma City (AAA) | Assigned to Oklahoma City (AAA) |
| Joe Biagini | P | 22.319 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Mason Hope | P | 20.290 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Daniel Camarena | P | 20.155 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Benjamin Hughes | P | 23.135 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Helpi Reyes | P | 20.260 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Ramon Del Orbe | P | 21.056 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Raul Fernandez | P | 22.295 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Joan Gregorio | P | 21.092 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Shane Broyles | P | 21.238 | Colorado Rockies | Asheville (A) | Assigned to Asheville (A) |
| Alex Smith | | 23.196 | New York Yankees | Charleston (sc) (A) | Assigned to Charleston (Sc) (A) |
| Brian Ellington | P | 22.252 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Stephen Johnson | P | 22.051 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Blake Logan | P | 21.092 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Dane Stone | P | 21.304 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Jose Reyes | | 22.100 | San Francisco Giants | Augusta (A) | Assigned to Augusta (A) |
| Andy Beltre | | 19.281 | Miami Marlins | Greensboro (A) | Assigned to Greensboro (A) |
| Charlie Short | P | 24.243 | New York Yankees | Charleston (sc) (A) | |
| Rafael De Paula | P | 22.020 | New York Yankees | Charleston (sc) (A) | |
| David Aardsma | P | 31.107 | Miami Marlins | New Orleans (AAA) | Signed to minor league contract |
| Scott Elarton | P | 37.050 | | | Signed by Sugar Land (Atlantic) |
