| Luke Putkonen | P | 26.096 | Detroit Tigers | Detroit Tigers (MLB) | Recalled from Toledo (AAA) |
| Duane Below | RP | 26.272 | Detroit Tigers | Toledo (AAA) | Optioned to Toledo (AAA) |
| Brett Pill | 1b | 27.339 | San Francisco Giants | Fresno (AAA) | Optioned to Fresno (AAA) |
| Pablo Sandoval | 3b | 26.003 | San Francisco Giants | San Francisco Giants (MLB) | Activated from DL |
| Mike Zagurski | P | 29.199 | Arizona Diamondbacks | Reno (AAA) | Outrighted to Reno (AAA) |
| Ralph Henriquez | C | 25.129 | - | | Released by Mariners |
| Daniel Sarria | P | 24.196 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Tyler Stubblefield | 3B | 24.269 | San Diego Padres | Fort Wayne (A) | Activated from DL |
| Stephen Carmon | SS | 22.176 | San Diego Padres | Eugene (A-) | Activated from DL |
| Uber Paz | P | 21.102 | San Diego Padres | Arizona Padres (Rk) | DL-60 Injured |
| Chris Robinson | C | 28.094 | Baltimore Orioles | Norfolk (AAA) | Activated from DL |
| Josh Donaldson | 3b | 26.249 | Oakland Athletics | Oakland Athletics (MLB) | Recalled from Sacramento (AAA) |
| Brandon Inge | 3b | 35.087 | Oakland Athletics | Oakland Athletics (MLB) | DL-15 Dislocated right shoulder |
| Garrett Olson | RP | 28.301 | New York Mets | Buffalo (AAA) | Outrighted to Buffalo (AAA) |
| Kelly Shoppach | c | 32.107 | New York Mets | New York Mets (MLB) | Traded from Red Sox to Mets for future considerations (Pedro Beato) |
| Trevor Rosenthal | RP | 22.077 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Recalled from Memphis (AAA) |
| Andrew Bailey | CL | 28.075 | Boston Red Sox | Boston Red Sox (MLB) | Activated from DL |
| Steve Johnson | RP-SP | 24.349 | Baltimore Orioles | Baltimore Orioles (MLB) | Recalled from Norfolk (AAA) |
| Troy Patton | RP | 26.345 | Baltimore Orioles | Baltimore Orioles (MLB) | DL-15 Sprained right ankle |
| Roberto Hernandez | SP | 31.349 | Cleveland Indians | Cleveland Indians (MLB) | Activated from restricted list |
| Josh Tomlin | RP | 27.299 | Cleveland Indians | Cleveland Indians (MLB) | DL-15 Right elbow inflammation |
| Justin Smoak | 1b | 25.252 | Seattle Mariners | Seattle Mariners (MLB) | Recalled from Tacoma (AAA) |
| Koyie Hill | C | 33.158 | Texas Rangers | Texas Rangers (MLB) | Signed to minor league contract |
| Jeff Mathis | c | 29.136 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Signed to 2-year contract extension thru 2014 (2015 option) |
| Yorvit Torrealba | C | 34.026 | Toronto Blue Jays | Toronto Blue Jays (MLB) | Signed to minor league contract |
| Alex Hinshaw | RP | 29.287 | San Diego Padres | San Diego Padres (MLB) | Designated for assignment |
| Tom Layne | RP | 27.285 | San Diego Padres | San Diego Padres (MLB) | Contract purchased from San Antonio (AA) |
| Danny Otero | P | 27.176 | San Francisco Giants | San Francisco Giants (MLB) | Recalled from Fresno (AAA) |
| Brad Penny | RP | 34.082 | San Francisco Giants | San Francisco Giants (MLB) | DL-15 Right shoulder impingement |
| Takashi Saito | RP | 42.181 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | DL-15 Strained left hamstring |
| Mike Zagurski | RP | 29.199 | Arizona Diamondbacks | Arizona Diamondbacks (MLB) | Contract purchased from Reno (AAA) |
| Mike Carp | 1b | 26.045 | Seattle Mariners | Seattle Mariners (MLB) | DL-15 Strained left groin muscle |
| Yuniesky Betancourt | 3b | 30.195 | - | | Released by Royals |
| Casey Coleman | SP | 25.042 | Chicago Cubs | Iowa (AAA) | DL-7 Injured |
| Matt Adams | 1B | 23.348 | St. Louis Cardinals | Memphis (AAA) | DL-7 Injured |
| Bill Murphy | P | 31.097 | Toronto Blue Jays | Las Vegas (AAA) | Activated from DL |
| Evan Crawford | RP | 25.346 | Toronto Blue Jays | Las Vegas (AAA) | DL-7 Injured |
| Angel Guzman | P | 30.243 | Los Angeles Dodgers | Albuquerque (AAA) | DL-7 Injured |
| Brock Peterson | 3B | 28.268 | St. Louis Cardinals | Memphis (AAA) | Signed to minor league contract |
| Shane Loux | RP | 33.001 | San Francisco Giants | Fresno (AAA) | Assigned to Fresno (AAA) for rehab |
| J.R. Towles | C | 28.185 | Minnesota Twins | Rochester (AAA) | Activated from DL |
| Dylan Owen | P | 26.033 | New York Mets | Buffalo (AAA) | DL-7 Injured |
| Logan Kensing | P | 30.042 | Pittsburgh Pirates | Indianapolis (AAA) | DL-7 Injured |
| Jose Lopez | dh | 28.264 | Chicago White Sox | Charlotte (AAA) | Signed to minor league contract |
| Bill Bray | RP | 29.070 | Cincinnati Reds | Louisville (AAA) | Assigned to Louisville (AAA) for rehab |
| Ryan Flaherty | 2B | 26.018 | Baltimore Orioles | Buffalo (AAA) | Assigned to Buffalo (AAA) for rehab |
| Miguel Socolovich | RP | 26.021 | Baltimore Orioles | Norfolk (AAA) | Designated for assignment |
| Devin Ivany | C | 30.018 | - | | Released by Nationals |
| Johnny Hellweg | P | 23.289 | Milwaukee Brewers | Huntsville (AA) | Activated from DL |
| Chris Reed | P | 22.086 | Los Angeles Dodgers | Chattanooga (AA) | DL-7 Injured |
| Matt Mangini | 1B | 26.236 | Arizona Diamondbacks | Mobile (AA) | Signed to minor league contract |
| Justice French | P | 23.012 | Cincinnati Reds | Bakersfield (A+) | DL-7 Injured |
| Egan Smith | P | 23.151 | Toronto Blue Jays | Dunedin (A+) | DL-7 Injured |
| Duanel Jones | 3B | 19.095 | San Diego Padres | Fort Wayne (A) | DL-7 Injured |
| Bobby Hansen | P | 22.240 | Washington Nationals | Hagerstown (A) | DL-7 Injured |
| Wirkin Estevez | P | 20.152 | Washington Nationals | Hagerstown (A) | Activated from DL |
| Drew Permison | P | 23.171 | Toronto Blue Jays | Vancouver (A-) | Transferred to 60-day DL |
| Michael Cuddyer | rf | 33.140 | Colorado Rockies | Colorado Springs (AAA) | Assigned to Colorado Springs (AAA) for rehab |
| Justin Toole | 2B | 25.338 | Cleveland Indians | Carolina (A+) | Assigned to Carolina (A+) |
| Carlos Rojas | SS-3B | 28.216 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Ryan Flaherty | 2B | 26.018 | Baltimore Orioles | Norfolk (AAA) | Assigned to Norfolk (AAA) for rehab |
| Bobby Coyle | LF | 23.161 | Los Angeles Dodgers | Chattanooga (AA) | Assigned to Chattanooga (AA) |
| Matt Marquis | LF | 22.173 | Boston Red Sox | Salem (A+) | Assigned to Salem (A+) |
| Anthony Rendon | SS | 22.069 | Washington Nationals | Harrisburg (AA) | Assigned to Harrisburg (AA) |
| Luis Sanz | C | 24.269 | Detroit Tigers | Erie (AA) | Assigned to Erie (AA) |
| Juan Diaz | ss | 23.245 | Cleveland Indians | Columbus (AAA) | Assigned to Columbus (AAA) |
| Brenden Webb | RF | 22.171 | Baltimore Orioles | Delmarva (A) | Assigned to Delmarva (A) |
| Brenden Webb | RF | 22.171 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Jerome Pena | 2B | 23.281 | Baltimore Orioles | Frederick (A+) | Assigned to Frederick (A+) |
| Chris O'Dowd | C | 21.314 | San Diego Padres | Eugene (A-) | Assigned to Eugene (A-) |
| Mike Zunino | C | 21.142 | Seattle Mariners | Jackson (AA) | Assigned to Jackson (AA) |
| Kevan Smith | C | 24.047 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Kevan Smith | C | 24.047 | Chicago White Sox | Winston-Salem (A+) | Assigned to Winston-Salem (A+) |
| Cameron Flynn | OF-P | 22.171 | Miami Marlins | Gulf Coast Marlins (Rk) | Assigned to Gulf Coast Marlins (Rk) |
| Jeremy Rodriguez | C | 22.349 | San Diego Padres | Lake Elsinore (A+) | Assigned to Lake Elsinore (A+) |
| Matt Skole | 3B | 23.015 | Washington Nationals | Potomac (A+) | Assigned to Potomac (A+) |
| Kelly Cross | C | 20.146 | Minnesota Twins | Elizabethton (Rk) | Assigned to Elizabethton (Rk) |
| Khayyan Norfork | 2B | 23.207 | Washington Nationals | Hagerstown (A) | Assigned to Hagerstown (A) |
| Jesus Aguilar | 1B | 22.045 | Cleveland Indians | Akron (AA) | Assigned to Akron (AA) |
| Ruben Sosa | 2B-CF | 21.325 | Houston Astros | Lexington (A) | Assigned to Lexington (A) |
| Andrew Douglas | LF-3B | 23.079 | Chicago White Sox | Bristol (Rk) | Assigned to Bristol (Rk) |
| Yasiel Puig | OF | 21.250 | Los Angeles Dodgers | Rancho Cucamonga (A+) | Assigned to Rancho Cucamonga (A+) |
| Guillermo Mota | P | 39.020 | San Francisco Giants | Arizona Giants (Rk) | Assigned to Arizona Giants (Rk) for rehab |
| Scott Swinson | P | 24.156 | Boston Red Sox | Gulf Coast Red Sox (Rk) | Assigned to Gulf Coast Red Sox (Rk) |
| Brandon Kintzler | RP | 28.013 | Milwaukee Brewers | Nashville (AAA) | Assigned to Nashville (AAA) |
| Scott Elbert | RP | 27.001 | Los Angeles Dodgers | Chattanooga (AA) | Assigned to Chattanooga (AA) for rehab |
| Jaime Garcia | P | 26.037 | St. Louis Cardinals | Memphis (AAA) | Assigned to Memphis (AAA) for rehab |
| Kyle Gibson | P | 24.296 | Minnesota Twins | Fort Myers (A+) | Assigned to Fort Myers (A+) |
| Brandon Workman | P | 24.001 | Boston Red Sox | Portland (AA) | Assigned to Portland (AA) |
| Chris Wilkes | P | 22.322 | San Diego Padres | Arizona Padres (Rk) | Assigned to Arizona Padres (Rk) |
| John Lamb | P | 22.035 | Kansas City Royals | Arizona Royals (Rk) | |
| Phil Klein | P | 23.106 | Texas Rangers | Myrtle Beach (A+) | Assigned to Myrtle Beach (A+) |
| Jordan Conley | P | 26.026 | Miami Marlins | Jupiter (A+) | Assigned to Jupiter (A+) |
| Mitch Lambson | P | 22.025 | Houston Astros | Lexington (A) | Assigned to Lexington (A) |
| Erik Johnson | P | 22.227 | Chicago White Sox | Kannapolis (A) | Assigned to Kannapolis (A) |
| Dylan Bundy | P | 19.272 | Baltimore Orioles | Bowie (AA) | Assigned to Bowie (AA) |
| Tayron Guerrero | P | 21.217 | San Diego Padres | Eugene (A-) | Assigned to Eugene (A-) |
| Lucas Giolito | P | 18.031 | Washington Nationals | Gulf Coast Nationals (Rk) | Assigned to Gulf Coast Nationals (Rk) |
| Brian Fuentes | P | 37.005 | St. Louis Cardinals | St. Louis Cardinals (MLB) | Placed on restricted list |
